Across the dose range (0.5–5 mg kg⁻¹), total distance travelled did not differ from vehicle (p > 0.2), supporting a lack of stimulant or sedative effect at therapeutic doses.
Rats (n = 10/group) were trained on a two‑object discrimination task. CTN (0.5 mg kg⁻¹) or vehicle was administered 30 min prior to the test phase (delay = 1 h). Discrimination index (DI) = (T novel – T familiar )/ (T novel + T familiar ) × 100. the substance couchtuner