For hands-on creation, modders and enthusiasts often use item editors. A popular one for Diablo 2 is "Diablo II: Item Editor" or similar tools designed for LoD.
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Even if you own original discs, using an ISO from an unknown source is unsafe. Better to from your physical discs using tools like ImgBurn (free, use carefully) or dd on Linux. For hands-on creation, modders and enthusiasts often use
If you lost your CD keys, Blizzard support may help if you have proof of purchase. Otherwise, you cannot legally play the classic version today without buying Resurrected or finding a second-hand old copy (keys may be used). Even if you own original discs, using an
If you're aiming to create a unique piece (not easily achievable through standard game mechanics):