Y158 Kristina ((new)) -

: Recent studies from the American Chemical Society (ACS) highlight a series of methyl-thiazole compounds that use this Y158 mechanism to improve drug potency while reducing side effects, such as cytochrome P450 inhibition.

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Based on the available information, "Y158" primarily refers to a specific protein residue () within the enzyme InhA of Mycobacterium tuberculosis . Research involving this residue is crucial for developing new treatments for tuberculosis. Scientific Context: Y158 in Tuberculosis Research : Recent studies from the American Chemical Society